prevention of calcium oxalate kidney stone - Stop Gout and Arthritis Pain and Soothe Sore Muscles with Tart Cherries
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Stop Gout and Arthritis Pain and Soothe Sore Muscles with Tart Cherries

Cherries have had a long history of being described as the "the healing fruit". Just as cranberries prevent urinary tract infections and an apple-a-day can keep the doctor away, tart cherries are known to stop gout and arthritis pain. But if tart cherries are so good, why haven't you heard more about them? Well first, the FDA doesn't want you to know.


If you take Vitamin C for gout as a dietary supplement, remember that it is reckoned to work better in a product that contains added citrus bioflavonoids. In addition, because it is excreted quickly, take it twice daily. To avoid excess acidity (lower pH) also take alkalizing minerals, or another alkalizing agent recommended by your doctor.


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 ' Stay tuned for the next article in our series on Arthritis, Symptoms of Arthritis". About the author: Written by John Robben of Ultimate Water Massage, Inc.

One complicating factor is that elusive fact that most people with hyperuricemia (excess uric acid)do not get gout. Another is that some people with normal uric acid levels do.

The cost of Arthritis is not only measured in the loss of quality of life, but it is also measured by dollars and cents as well. It is estimated that over $150,000 is lost by an individual over the course of a lifetime due to the debilitating effects of Arthritis. This is totaled by lost wages, medical treatments, and the cost of medically based needs and care.


In other patient groups there were reductions in attacks and improvement in tophi reduction. Tophi are those knobbly shaped, awkward looking, lumps of MSU crystals that often develop in longer term gout sufferers.

Other encouraging statements were that all extension trial patients who had responded earlier to treatment and who were on the every two week course maintained normal uric acid levels, (some were new joiners). 70% of those on an every four week course who had responded earlier to treatment, maintained normal uric acid levels.

The leading super fruit company in the U.S. is Fruit Advantage. The company offers a complete line of super fruit products including tart cherry capsules.

The overall conclusion is that Arthritis is a seriously unbearable condition that causes chronic pain and weakness. It does not only affect seniors, but forms of Arthritis also plagues children. There are over 100 forms of Arthritis and all Arthritis sufferers share one thing in common, chronic joint pain. The top three common forms of Arthritis include Osteoarthritis, Rheumatoid Arthritis, and Gout. We have seen that Arthritis isn't cured, but managed.
Some steps and treatment plans used by Arthritis sufferers include:


It also reached the well-known and accepted conclusion that hypertension (high blood pressure) and obesity are risk factors for gout. And one other very different conclusion from the conventional wisdom about purines -- purine intake, with the exception of alcohol, was NOT associated with a risk of gout.

Secondly, although tart cherries have been studied for years, no real effort was ever really made to promote the health benefits of the tart cherry. However, the cherry growers are really getting the word out about cherries to the world.

Should you take Vitamin C for gout? The answer is probably yes, but read on for a possibly relevant caution. Gout cures require that uric acid levels be reduced. Vitamins and drugs work in two ways to reduce uric acid levels. One is restricting its supply by inhibiting purine breakdown into uric acid, the other is improving uric acid's breakdown into the urine. Vitamin C is thought to be a uric acid excretory, not an inhibitor. Improving excretion may be more important than reducing production.

Cherries are a natural and high source of Melatonin. This helps to regulate circadian rhythms and maintain nightly sleep patterns. Also, cherries have been shown to have naturally occurring anthocyanins. Although, anthocyanins are present in also any number of colored fruit, the unique make-up of the compounds found in the tart cherry helps to fight joint pain. So in other words, the compounds in the tart cherry are natural COX-1 and COX-2 inhibitors.

Such a rapid change concerned the authors of one study in the 1970's who had recorded that mega doses of Vitamin C (4,000 mg and 8,000 mg daily) reduced uric acid levels significantly, and by more than in the 2005 study. However, as far as Vitamin C induced changes in uric acid levels is concerned, this triggering has not been reported in any study.

Pegloticase's answer to the excess uric acid level problem is to remove it by ingeniously converting uric acid into something else, a substance called Allantoin. Allantoin is more soluble and better excreted than uric acid. The principle comes from the way most animals do it. They do it by converting UA to Allantoin, but this is something humans cannot do naturally. Hence the formulation of Pegloticase.

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SIDE EFFECTS Of course Pegloticase has caused side effects, in the extension trial in about 1 in 5 patients. The developing company has said that most were mild, moderate, or controllable. But in some cases more severe side effects have been described as including chest and back pains, muscle cramps, sweating and flushes.

Arthritis: What it Is

Basically, Arthritis is inflammation of the joints. There are currently over 100 forms of Arthritis and remarkably, that number continues to rise. The most common forms of Arthritis include: Osteoarthritis, Rheumatoid Arthritis, and Gout (see our next article, "Symptoms of Arthritis" for more information). Osteoarthritis is the result of degenerative joint disease, or simply "wear and tear" on the joints. Rheumatoid Arthritis is the result of an over active Immune System that results in inflammation. Gout is the oldest form of Arthritis and is the result of too much Uric Acid. The Uric Acid deposits crystals in the joints, leading to "Gouty Arthritis". The joint pain, inherent to all Arthritis sufferers, is referred to as "Arthralgia". Not only are the joints susceptible to attack, but the surrounding muscles, tissues, and organs are vulnerable to the effects of Arthritis as well. In fact, Arthritis has been known to attack the heart, kidneys, lungs, and liver.


However, restricting purines in your diet is not difficult, so it is still worth doing. The conventional wisdom may be correct. Uric acid level tests should tell if a low purine diet works for you.

In the world of natural gout remedies, uric acid's removal can be improved by making it more soluble. This is achieved by drinking lots of water and by raising body pH levels in various ways.

Many people mistakenly believe that Arthritis is a disease that only affects the elderly. This simply isn't the case. Yes it's true that seniors, especially senior women, are effected the greatest by Osteoarthritis, yet the average age for onset of Arthritis is 47 years old, and sufferers are generally afflicted between the ages of 20-50. Sadly, even infants have been diagnosed with forms of Arthritis.


One of the most devastating effects of Arthritis has to be that it is a chronic condition. Arthritis is so weakening that it only grows worse with time. In fact, Arthritis is so detrimental that of the diseases that instill chronic physical disabilities, Arthritis is second only to Heart Disease.


' Losing Weight (thereby reducing stress and strain on the joints)
' Increasing their Nutritional Intake
' Reducing Stress (both physical and emotional)
' Participating in Gentle Stress Free Exercises such as Stretching
' Using both Hot and Cold Therapies
' Protecting Joints by use of Splints and Braces
' Drug Therapies
' Surgery


A few studies over the past 30 years have concluded that Vitamin C will reduce the uric acid level. They have differed in the amount of Vitamin C given to study participants. A U.S. study of 184 non-smokers, published in 2005, concluded that the amount required to achieve a serum (blood) uric acid level reduction was 500 mg daily. (The Vitamin C was taken as a supplement). This is not a mega dose.

 
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If you suffer from Arthritis, don't give up. There are many people who are discovering that with the proper management and health care provisions, they can live better, healthier, and pain free lives.


In addition to fighting joint pain, research also shows tart cherry juice helps to soothe sore muscles due to physical exercise. According to a study published in the British Journal of Medicine in June 2006, found that a drink made with tart cherry juice proved effective in reducing exercise-caused muscle pain and exercise-induced strength loss. The study was conducted on college athletes and the results basically found that the tart cherry drink helped to reduce pain and strength loss when compared to the placebo.

31% of patients who had not reduced tophi at the end of these phase 3 trials did show tophi reduction in the extension trial. It would seem that the longer a gout sufferer is able to take Pegloticase the more successful it may be, in tophi cases at least.

b>Arthritis: Its Debilitating and Detrimental Effects Did you know that Arthritis is one of the most disabling diseases? It's true! Arthritis currently affects more than 40 million Americans and that figure is expected to rise to 60 million by the year 2,020. It is imperative that you read this article and find out what this devastating disease is truly about.


In fact, just a few years ago the FDA threatened over two dozen cherries companies for sharing information on the research conducted by the USDA how cherries help fight gout and joint pain. So much for freedom of speech in America. This is something similar to what happened to the cranberry sellers several years ago. They were also threatened. But look at it today, research shows that cranberries can fight urinary tract infections. Thanks for the freedom of speech in America.

In May 2008 the U.S. based company developing Pegloticase made another upbeat statement assessment of what they have learnt in its Phase 3 and open label extension trials. Note that Pegloticase still awaits approval from medical authorities so I am writing here about a new gout drug that is still under development.

0.5 mg/dL is a useful reduction but for most people probably not a natural remedy for gout, although the 0.5 mg/dL figure is an average and some participants did better. But a 0.5mg/dL reduction will not be enough to reduce uric acid below the 6.0 mg/dL level at which the MSU crystals may dissolve. However, when combined with other vitamins for gout, a low purine diet and other natural remedies for gout, it could be.

May was a good month for gout sufferers. Febuxostat, (EU trade/brand name Adenuric), the first new major drug medication for gout in over 40 years, was approved for marketing in member countries of the European Union.

This suggests that progression of the disease may be contained in difficult-to-treat cases, and therefore may not cause other medical conditions such as kidney stones heart disease and hypertension.

It has been having a decent degree of success. Elimination of gout attacks In its most recent statement the developing company's most significant remark was that the extension trial group receiving Pegloticase every two weeks, there were only four gout attacks among those who had been administered Pegloticase (8 mg) every fortnight for two months, in subsequent months. And none in this group had a gout attack after five months of Pegloticase treatment, in following months. All were patients who had been through a phase 3 trial.

Previously it has been thought that the amount needed was at least 4,000 mg (4 grams) daily. For example, Dr. Robert Atkins in his book " Vita Nutrient Solutions," recommended 5,000 -10,000 mg as part of his formula natural remedy for gout.

In addition to fresh cherries and cherry drinks you can also choose from tart cherry juice concentrate and tart cherry capsules. One of the benefits of tart cherry juice concentrate is it takes approximately 100 cherries to make just one ounce of tart cherry juice. So the tart cherry juice is a highly concentrated way to get your daily dose of cherries. www.traversebayfarms.com

In the 2005 study by how much did 500 mg of Vitamin C reduce their uric acid level? It found an average, across all participants, reduction of about 10% (0.5 mg/dL). In addition, reductions were larger among participants who had higher levels of uric acid at the start of the study. Participants took the 500 mg daily level for two months. Those who were given a placebo (i.e. not Vitamin C) showed a slight increase in uric acid levels.

Pegloticase is getting closer to an application for approval by the U.S. FDA. Its developers hope to apply for a Biologics Licence Application in September 2008, and begin marketing it in 2009.

VITAMIN C AS A GOUT PREVENTOR If 500 mg daily of Vitamin C can reduce uric acid levels, then Vitamin C ought to act as a preventative gout vitamin too. A Taiwan study of males in the late 1990's examined the weight, diet and lifestyles of gout and non-gout sufferers in Taiwan. It concluded that Vitamin C, folic acid (folate) and fibre were protective against gout.

Tart cherry capsules are another way to get tart cherries. Tart cherry capsules are made with tart cherry powder. The tart cherry powder is made using the freeze-dried process. The freeze dried process is one of the best ways to get tart cherry powder. The reason is the freeze-dried process captures 100% of the nutritional value of the tart cherry.

HOW PEGLOTICASE WORKS What makes Pegloticase a very interesting, and more importantly, a hopeful new gout drug, is the way it works. All drugs used in gout try to cure or alleviate the disease by reducing the body's uric acid (UA) levels. They do this by either inhibiting its production or making it easier to remove.

THE CAUTION Rapid changes in uric acid levels can trigger a gout attack. This rapid change can be brought about by many factors in addition to possibly mega doses of Vitamin C and by drugs such as probenecid and sulfinpyrazone. People who are susceptible to gout must consider these rapid changes.

1,000 MG PLUS DOSES If you wish to try Vitamin C for gout in doses over 1,000 mg as part of a natural gout remedy discuss it with your doctor or a qualified naturopathic doctor. The 500 mg level is below the British government's 1,000 mg (1 gram) recommended upper safety level safety limit for Vitamin C. It is half of the maximum amount (1,000 mg) in a Vitamin C tablet sold in the U.S. and many other countries.

TRIAL SUCCESS WITH DIFFICULT TO TREAT GOUT PATIENTS Pegloticase is significant because its trials have focused on gout patients who have not had success with other gout drugs, or who have medical conditions which prohibit the use of them. Thus it has been tackling harder-to-treat gout cases, not the easier ones. Hard to treat cases are a significant percentage of the gout sufferer universe.

NB. The contents of this article contain medical information not medical advice. Please always discuss gout remedies with your doctor or other health care professional, before implementing any treatment.


 
 
     
 
 





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