purine analog definition - Symptoms of Gout and its Causes
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Symptoms of Gout and its Causes

Gout is also known as crystal-induced arthritis. It is a medical condition that sets in when uric acid crystals collect on the joints. At the first stage, gout usually affects the large joints in the big toe. Gradually it can spread to other parts of the body, like the ankles, the instep, the heels and the knees, the wrists and fingers of the hand and the elbows. In severe cases, even the shoulders, hips or spine can be affected. Gout does not spread from one joint to the next. Uric acid is a metabolic end product that is formed at the time the body breaks down purines present in certain food items. In normal conditions, the uric acid gets dissolved in the blood and gets eliminated from the body through the kidneys into the urine. However, people having a propensity for gout have such high levels of uric acid in their blood that the acid precipitates out in the form of crystals. The crystals get accumulated on the joints and other tissues, leading to inflammation and excruciating pain. A chronic condition can lead to the formation of tophi lumps formed under the skin due to large deposits on severely affected joints of the elbow, fingers and toes, and even on the external pinna.


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Another medical condition, referred to as the pseudo-gout, results from the deposits of calcium-based crystals in the joints. In almost 90 percent of incidences of gout, men over the age of 40 and menopausal women are affected. An "episode" often takes place during the night. Within 12 to 24 hours of the onset, the afflicted joint becomes severely inflamed and starts to ache rigorously. The gout attack usually lasts about five to 10 days.

Linda L. Patterson is a living testimony of the soothing affects of cherries on her joint pain. 'I enjoy crocheting and lately my hands have been so painful, I couldn't crochet for more than about 30 minutes.', says Patterson. In an attempt to find relief from her pain, she located Fruit Advantage Tart Cherry capsules, a supplement made from red tart cherries. 'Within the first week of taking the tart cherry capsules my hands felt so much better.', says Ms. Patterson. 'I am now able to crochet without the pain in my hands.'

There are many natural products that can reduce serum uric acid concentration. Gout sufferers are advised to eat plenty of fiber-rich vegetables (preferably raw) and fresh fruits, as they contain low levels of purines and they are also a great source of vital nutrients. Among all fruits, cherries seem to be the best natural remedy for gout. Apart from being irresistibly delicious, cherries have anti-inflammatory, sedative and analgesic properties, and they can considerably ameliorate the clinical manifestations of gout. A frequent intake of cherries can considerably reduce the duration and the intensity of gout attacks, by normalizing uric acid levels inside the body. Recent studies have revealed that by including cherries in their diet, gout sufferers are able to eliminate more uric acid through urine. Thus, cherries act as a purgative agent, aiding the process of excretion.

One of the most common problems that can be associated with gout and kidney function is blockage of these organs. This blockage occurs in the tubular filters that allow the kidneys to rid the body of unwanted materials. When they become clogged with uric acid crystals, the kidneys are unable to perform their proper function. When this happens, kidney failure can occur. This condition must be treated right away in order to restore proper function to the kidneys, and to the body.

Gout is a condition that results when crystals of uric acid are deposited body tissues, and is characterized by an overload of this acid. It causes joints to become inflamed and is often very painful. Chronic gout can lead to deposits of hard lumps in and around the joints.

Gout has the distinction of being one of the most recorded medical illnesses throughout history. It is also said to be related to an inherited abnormality in the ability for the body to process uric acid. Uric acid is a break-down of pureness that is part of the many foods frequently consumed. This inability to process uric acid can cause the painful attacks of gout, along with the other serious conditions mentioned above.

The Signs and Symptoms of Gout include: Hyperuricemia Presence of uric acid crystals in joint fluid More than one attack of acute arthritis

As a result, patients with gout can experience decreased kidney function and kidney stones, which are also very painful. When these problems occur, they must be treated immediately.

Sour cherries seem to reduce gout pain and inflammation and they also contain natural antioxidants that can decongest the arteries clogged with uric acid crystals. Sour cherries are rich in vitamin A, they contain very few calories and they can be safely introduced in any gout diet. Recent studies have revealed that by consuming around 100 grams of cherries each day, gout sufferers can experience a rapid amelioration of their symptoms. Although it is best to consume them raw, cherries can also be introduced in various recipes. Thanks to their remarkable qualities, cherries should be included in any diet.

In addition to the health benefits offered by cherries, many people are just eating the fruit for the taste. John Simms, a life-long resident of Indianapolis, Indiana, eats cherries for the convenience and taste. 'As a short-haul truck driver, my diet isn't the best, I would eat fast food every day. A year ago, my wife bought some dried cherries and I began eating them to keep my weight down. Now I eat a handful of cherries instead of eating fast food.'

Erratic lifestyle, alcohol abuse, purine-rich diet and excess weight

Surgery or sudden injury, severe illness

Proper understanding of the cause and symptoms of gout can help in achieving a successful cure for gout attacks. Want to learn more about Gout Symptom Sign?, feel free to visit us at: http://www.about-goat.info/Articles/Gout_Symptoms.php

 
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About the author:
Tony Anderson is a freelance writer.

Both sweet cherries (dark cherries) and sour cherries (ruby-red cherries) have proved to be very benefic for gout sufferers. Sweet cherries contain few calories and are rich in natural fibers. Sweet cherries contain melatonin, a chemical that has sedative and analgesic effects. Thus, the intake of sweet cherries can also ease recurrent gout pain. In addition, this type of cherries contains a powerful natural antioxidant that acts similarly to vitamin C. Sweet cherries can also lower the levels of inflammatory substances such as nitric oxide and C-reactive protein, chemicals that are related to gout, diabetes and heart disease.

The probable causes of gout include: Genetic defects in metabolism resulting in hyper-production and retention of uric acid in the blood

Not only are cherries a great way to maintain a healthy body they are a natural product. According to Andrew LaPointe, Director of Marketing for Traverse Bay Farms, www.traversebayfarms.com 'many of our customers are looking to eat healthier and fruit products fit this trend. It's certainly better than fast food.' Traverse Bay Farms sells Fruit Advantage Tart Cherry capsules and cherry juice concentrate.

Gout is a type of arthritis caused by the excessive accumulation of uric acid inside the organism. In large amounts, uric acid forms crystals which deposit in various regions of the body, causing inflammation, pain and swelling of the joints. Uric acid is a waste product that results from purine metabolism. Although most cases of gout are hereditary, occurring due to genetically acquired renal dysfunctions which determine an inappropriate elimination of uric acid, gout is more likely to occur in people who consume large amounts of purine-rich foods. Thus, an appropriate diet and lifestyle improvements can successfully alleviate the symptoms of gout and can actually reverse the undesirable effects of the disease.

Kidney failure leading to hampered elimination of uric acid from the body Diuretic medications employed in the treatment of heart failure and diabetes.

The little red fruit that has been enjoyed by countless millions offers more than great taste. Are cherries truly fruit for a healthy you? Recent studies have revealed that cherries offer an assortment of health benefits including the ability to offer natural relief from joint pain caused from gout, arthritis and joint inflammation.

Not everyone who has gout will experience such severe symptoms. Some patients may only develop elevated blood uric acid levels, a condition that is known as hyperuricemia. These patients may not have the arthritic joint pain and other symptoms. The actual term "gout" is often used in reference to the painful joint attacks.

Gout, when referred to in this way, is usually an extremely painful arthritic attack with a rapid onset of joint inflammation. The deposits of uric acid crystals in the joint fluid that helps to facilitate proper motion precipitate this inflammation. When this occurs, this fluid is unable to correctly do its job because the crystals are in the way. Because of this, the joints are not able to move properly, and movement becomes very painful.

Arthritis that develops in 1 day Attack of arthritis in only one joint, usually the toe, ankle, or knee A painful joint that is swollen, red, and warm

While hyperuricemia and gout often occur together, there is currently not medical evidence that shows their exact relationship. Some patients with hyperuricemia do not develop gout, while others with repeated gout attacks show normal or low blood uric acid levels. Still, it continues to be a common problem, and should be treated to keep other more serious conditions from occurring. Because it is painful, and, therefore, very distinguishable, it can usually be easily diagnosed and quickly treated.

So what makes the tasty red fruit so beneficial? The wonder of the cherry is the anthocyanins. According to research from Michigan State University tart cherries contain anthocyanins and bioflavonoids, which inhibit the enzymes Cyclooxygenase-1 and -2, and prevent inflammation in the body. These compounds have similar activity as aspirin, naproxen and ibuprofen. Further investigations revealed that daily consumption of tart cherries has the potential to reduce the pain associated with joint inflammation. Many consumers are choosing to drink cherry juice, eat cherries or consume tart cherry pills to starve off the pain of gout, arthritis and joint inflammation.

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