definition of purines and pyrimidines - Gout Pain Relief
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Gout Pain Relief

Gout is caused by the increase in the amount of uric acid in the blood. Uric acid is normally removed from the body through the urine, however if it is not excreted it can form crystals, which irritate body tissues like the lining of joints. This will in turn cause inflammation and pain, which is often quite severe.


Tart cherry capsules are another way to get tart cherries. Tart cherry capsules are made with tart cherry powder. The tart cherry powder is made using the freeze-dried process. The freeze dried process is one of the best ways to get tart cherry powder. The reason is the freeze-dried process captures 100% of the nutritional value of the tart cherry.


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 In other patient groups there were reductions in attacks and improvement in tophi reduction. Tophi are those knobbly shaped, awkward looking, lumps of MSU crystals that often develop in longer term gout sufferers.

This suggests that progression of the disease may be contained in difficult-to-treat cases, and therefore may not cause other medical conditions such as kidney stones heart disease and hypertension.

Pegloticase's answer to the excess uric acid level problem is to remove it by ingeniously converting uric acid into something else, a substance called Allantoin. Allantoin is more soluble and better excreted than uric acid. The principle comes from the way most animals do it. They do it by converting UA to Allantoin, but this is something humans cannot do naturally. Hence the formulation of Pegloticase.

- NSAID's - in low doses. - Colchicine- in low doses. - Allopurinol (Zyloprim): decreases production of uric acid by the body.

Your health is your responsibility...and you have to make a choice between a life long intake of chemicals that will necessarily damage your system, or use plain old common sense and go for an alternative and much safer (and cheaper) solution. In fact there are dozens of natural compounds that can maintain a healthy level of uric acid in your body without damaging it; but very few, if any, perform as Uricinex does.

If a person is on many medications, which can cause gout, changing these may help. One common cause is diuretic medications, which decrease leg swelling or edema. Many older individuals are on these medicines and if they get a gout attack they must remember this fact.

TRIAL SUCCESS WITH DIFFICULT TO TREAT GOUT PATIENTS Pegloticase is significant because its trials have focused on gout patients who have not had success with other gout drugs, or who have medical conditions which prohibit the use of them. Thus it has been tackling harder-to-treat gout cases, not the easier ones. Hard to treat cases are a significant percentage of the gout sufferer universe.

Cherries are a natural and high source of Melatonin. This helps to regulate circadian rhythms and maintain nightly sleep patterns. Also, cherries have been shown to have naturally occurring anthocyanins. Although, anthocyanins are present in also any number of colored fruit, the unique make-up of the compounds found in the tart cherry helps to fight joint pain. So in other words, the compounds in the tart cherry are natural COX-1 and COX-2 inhibitors.

The relief of pain is remarkable with some of the anti-inflammatory medicines also called NSAIDS or non-steroidal anti-inflammatory medications. The typical example is indomethacin or ibuprofen. Applying local ice or heat may sometimes help as well as keeping the joint without moving or bumping into objects.

Other encouraging statements were that all extension trial patients who had responded earlier to treatment and who were on the every two week course maintained normal uric acid levels, (some were new joiners). 70% of those on an every four week course who had responded earlier to treatment, maintained normal uric acid levels.

In some situations steroid medications like prednisone may be needed. The steroids will decrease the inflammation and decrease the chemical responses that cause pain. It is important to know that there are many side effects from all of the medications and you must discuss these with your healthcare provider.

Secondly, although tart cherries have been studied for years, no real effort was ever really made to promote the health benefits of the tart cherry. However, the cherry growers are really getting the word out about cherries to the world.

Pain can be treated with the following medication: - Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, naproxen, or indomethacin. Aspirin based medication should be avoided as aspirin could worsen the situation as it prevents the kidneys from eliminating uric acids. Do not take Aspirin based compound if you have a gout attack.

31% of patients who had not reduced tophi at the end of these phase 3 trials did show tophi reduction in the extension trial. It would seem that the longer a gout sufferer is able to take Pegloticase the more successful it may be, in tophi cases at least.

Uricinex is a proven, naturally potent product that is effective in maintaining healthy levels of uric acid, yet still safe enough to take everyday. Having no chemically generated compounds, fillers, or artificial additives and unlike

In May 2008 the U.S. based company developing Pegloticase made another upbeat statement assessment of what they have learnt in its Phase 3 and open label extension trials. Note that Pegloticase still awaits approval from medical authorities so I am writing here about a new gout drug that is still under development.

In addition to fighting joint pain, research also shows tart cherry juice helps to soothe sore muscles due to physical exercise. According to a study published in the British Journal of Medicine in June 2006, found that a drink made with tart cherry juice proved effective in reducing exercise-caused muscle pain and exercise-induced strength loss. The study was conducted on college athletes and the results basically found that the tart cherry drink helped to reduce pain and strength loss when compared to the placebo.

- Stop the pain from reaching your brain. . For that you will be prescribed a painkiller among a whole battery of products. - Change the behavior of your inner organs hoping either to reduce levels of uric acid secretions or increase the expulsion of that acid uric.

May was a good month for gout sufferers. Febuxostat, (EU trade/brand name Adenuric), the first new major drug medication for gout in over 40 years, was approved for marketing in member countries of the European Union.

HOW PEGLOTICASE WORKS What makes Pegloticase a very interesting, and more importantly, a hopeful new gout drug, is the way it works. All drugs used in gout try to cure or alleviate the disease by reducing the body's uric acid (UA) levels. They do this by either inhibiting its production or making it easier to remove.

 
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It has been having a decent degree of success. Elimination of gout attacks In its most recent statement the developing company's most significant remark was that the extension trial group receiving Pegloticase every two weeks, there were only four gout attacks among those who had been administered Pegloticase (8 mg) every fortnight for two months, in subsequent months. And none in this group had a gout attack after five months of Pegloticase treatment, in following months. All were patients who had been through a phase 3 trial.

SIDE EFFECTS Of course Pegloticase has caused side effects, in the extension trial in about 1 in 5 patients. The developing company has said that most were mild, moderate, or controllable. But in some cases more severe side effects have been described as including chest and back pains, muscle cramps, sweating and flushes.

In the world of natural gout remedies, uric acid's removal can be improved by making it more soluble. This is achieved by drinking lots of water and by raising body pH levels in various ways.

Colchicine is typically used if the first line medications like NSAID's do not help but most people have relief of pain ultimately. Even if no medicines are taken the attack will subside in a few days. However if repeated attacks occur there can be lasting damage.

- Probenecid (Benemid), which is a Uricosuric agents that increase elimination of uric acid by the kidneys. Whether your doctor prescribed Non Steroid Anti Inflammatory Drugs (such as Ibuprofen), corticosteroids or Uricosuric agents you have to assume that those drugs are for life.... It does not take much imagination to realize how much damage this life consumption of these drugs is going to cause to your health... More so if, because of age or for whatever other reason, you are under treatment for another illness and are consuming

Pegloticase is getting closer to an application for approval by the U.S. FDA. Its developers hope to apply for a Biologics Licence Application in September 2008, and begin marketing it in 2009.

In some gout attacks patients may need joint fluid removed for analysis and during the process can have local numbing medicines injected into the joint. These numbing medicines are also called local anesthetics. Sometimes steroids are injected into a joint to decrease the inflammation.

The leading super fruit company in the U.S. is Fruit Advantage. The company offers a complete line of super fruit products including tart cherry capsules.

Cherries have had a long history of being described as the "the healing fruit". Just as cranberries prevent urinary tract infections and an apple-a-day can keep the doctor away, tart cherries are known to stop gout and arthritis pain. But if tart cherries are so good, why haven't you heard more about them? Well first, the FDA doesn't want you to know.

The real secret behind gout treatment. And how Uricinex fits in... First of all, never assume because of a joint pain that you have Gout. Too many other illnesses can appear as a gout attack. You may have high level of acid uric in the blood and never develop Gout, or have a Gout attack even with normal levels of uric acid. Suspected Gout should always, and only be diagnosed by a Doctor because left untreated, it can eventually lead to arthritis, tissue deposits, nerve damage, acute inflammatory response, and kidney failure. Once diagnosed traditional medicine does not have other goal than:

antidepressants, tranquilizers, antibiotics, antihistamines and whatnot ... In the long run such interaction of so many drugs can be even be fatal. In fact what conventional medicine does is control the excesses of uric acid by delaying its devastating effects over time...

- Corticosteroids: Steroid tablets can also be used to reduce pain and inflammation if problems occur when using these other drugs With proper treatment a gout attack can be controlled within 12 to 24 hours. Once a gout attack is under control, treatment will ususually be stopped after a few days. Your Doctor will prescribe any combination of the following:

Causes Of Gout provides detailed information on Causes Of Gout, Foods That Cause Gout, Gout, Gout Home Remedy and more. Causes Of Gout is affiliated with Laser Printers.

As with all medications make sure you do not have an allergy to them and sometimes taking the medicine with food may decrease stomach upset or gastric distress, especially medicines like steroids.

NB. The contents of this article contain medical information not medical advice. Please always discuss gout remedies with your doctor or other health care professional, before implementing any treatment.

pharmaceutical drugs, Uricinex??? has no negative side effects. Omar Martinez is an independent health market analyst specialized in natural health supplements and owner of many health related sites among them:

In addition to fresh cherries and cherry drinks you can also choose from tart cherry juice concentrate and tart cherry capsules. One of the benefits of tart cherry juice concentrate is it takes approximately 100 cherries to make just one ounce of tart cherry juice. So the tart cherry juice is a highly concentrated way to get your daily dose of cherries. www.traversebayfarms.com

In fact, just a few years ago the FDA threatened over two dozen cherries companies for sharing information on the research conducted by the USDA how cherries help fight gout and joint pain. So much for freedom of speech in America. This is something similar to what happened to the cranberry sellers several years ago. They were also threatened. But look at it today, research shows that cranberries can fight urinary tract infections. Thanks for the freedom of speech in America.

- Colchicine: Colchicines is an alternative medicine, which eases the symptoms of gout attacks. Colchicine is usually taken if patients have problems with anti-inflammatory painkillers

http://www.naturalherb4u.com/uricinex.html


 
 
     
 
 





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